Frequently asked questions

What are the most common potential and positive effects (areas of improvement) of low-dose lithium orotate supplementation?

Happier state of mind and more positive attitude

Depression all types, significantly reduced

Anxiety and panic significantly reduced

Less worry and repetitive intrusive thoughts

Relaxing comes easier

Sleep Improved: Better, deeper and restorative sleep

Thinking with focus significantly improved

Peace of mind

Social interactions significantly improved

Memory and learning significantly improved

Energy boosted and a more even flow of energy is present

Headaches all types significantly improved or resolved through prevention

Pain reduced: all areas, back and neck, potentially, mental, emotional and physical

Joint Pain and Stiffness reduced and greater mobility of movement

Muscle spasms and tension significantly reduced

Skin and hair look and feel healthier

Who created Lithium Orotate?

 German Physician, Dr. Hans Nieper, is generally acknowledged for the synthetic creation of lithium orotate within a laboratory in the late 1960’s and experimented and published in his first study, appearing in 1973 in Agressologie, "The clinical applications of lithium orotate. A two years study".

How much experience does Dr. Millar have with lithium orotate?

Dr. Millar has over 5,000 hours of research, writing and speaking on the topic of lithium orotate, and well over 1,000 hours consulting individuals by phone.

What should I expect from my first microdose serving of lithium orotate?

The good news, approximately 95% of first-time microdose experiences are either positive or neutral, (without effect and without an issue). If you follow the path, we have laid out for you and start with the most conservative plan you may experience the following:

1. Most commonly you feel a little more relaxed, focused with an improvement of your mood.
2. Less common, but certainly it happens, you feel no change at all. Your responses will be determined by how much lithium you take. If you don’t take enough, you may not see or feel the results. It is common to feel nothing at all from a small initial serving of lithium orotate.

What is the main difference between pharmaceutical lithium (RxLi) and lithium orotate?

There are many differences but the main one, the one that really matters, is the difference of the cellular absorption rates, between the two. RxLi is poorly absorbed, while lithium orotate is readily absorbed, 100% within the cells of the body, while RxLi is very poorly absorbed within the cell.  With lithium orotate, you are able to take very small amounts and get big results.

Can everyone, even children and the elderly, try a lithium microdose of 50mcg-250mcg?

 Yes, BUT, before anyone tries a micro-dose of lithium, they MUST read the section on safety, regarding the contra-indications for individuals who should NOT take lithium.

If you are on this list you are advised to seek supervision from your doctor and preferably a physician or expert trained in lithium administration before you utilize lithium orotate. Remember, you are cautioned not to go up beyond a microdose of 1 mg, of pure elemental lithium without supervision, if you are on the Contraindications list.

Does everyone get the same results from lithium orotate?

No. There is a wide range of results experienced by different individuals.

What is considered to be a lithium microdose?

 A microdose is a minute amount of lithium, 1mg or less, generally measured in micrograms (mcg). So generally speaking, we are talking about amounts from 50 mcg - 1000 mcg. 1000mcg = 1mg.

Are the results achieved with lithium orotate dependent upon the serving size ingested?

 Yes. A fundamental truth about lithium is that it has been scientifically proven to produce a multitude of various chemical and biological reactions occurring at various lithium blood levels.

What serving size of lithium orotate should you consume to achieve the results you are seeking?

 That depends upon multiple variables that must be calculated on an individual basis, based upon the individual's “unique biochemical individuality”, considering factors such as age, weight, sex, pre-existing disease(s), pharmaceutical drug interactions, sensitivity to lithium administration and supplementation. For this reason, we have created the Lithium Micro-dose and Low-dose Workbook.

 

What are the lowest lithium levels examined, and found to positively effect human beings?

 Lithium is naturally occurring in aquifers and surface water all over the world. Examined throughout the worlds, naturally occurring lithium in the municipal drinking water, in amounts as low as 50 – 250 micrograms (mcg) appear to be enough to lower crime and suicide rates for example. In a double-blind placebo-controlled study, elderly patients received a microdose of lithium, and found enhanced cognitive function when compared to the placebo group. 

What are the higher levels of lithium beneficial for, and used to treat in modern medicine?

The conditions known as mood disorders use the highest lithium levels.  Mood disorders include bipolar disorder, depression, anxiety, and premenstrual syndrome to name a few.

Who should NOT take lithium without supervision.

Anyone on the following list of Contraindications.

Contraindications for Individuals Who Should Not Take Lithium without supervision!

Some of the individuals on this list, may low-dose with lithium, but only under supervision.

1.      Mild Kidney/Renal Disease/Impairment (OK under doctors’ supervision)

2.      Moderate to Severe Kidney/Renal Disease/Impairment

3.  Addison's disease. (OK under doctors’ supervision)

4.      Brugada Syndrome – Heart palpitations (OK under doctors’ supervision)

5.      Individuals with Hyponatremia (Low Sodium Levels)

6.      Individuals with Dehydration or Volume Depletion

7.      Pregnant Women (Particularly First Trimester) (OK under doctors’ supervision)

8.      Breastfeeding Women (OK under doctors’ supervision)

9.      Organic Brain Syndrome (TBI, or neurodegenerative disease) (OK w/ supervision)

10.  Thyroid Disease - (OK under doctors’ supervision)

11.  Nephrogenic Diabetes Insipidus (NDI) (OK under doctors’ supervision)

12.  History of Neuroleptic Malignant Syndrome (NMS) or Risk When Combined with Haloperidol

13.  Children Younger Than 7 Years (OK under doctors’ supervision)

14.  Cystic fibrosis (OK under doctors’ supervision)

15.  You are taking prescription lithium. (OK under doctors’ supervision)



16.  You are on medications that may interact with lithium. (OK under doctors’ supervision)

17.  You are giving it to infants, children, or the elderly. (OK under doctors’ supervision)

18.  You are taking diuretics or ACE inhibitors. (OK under doctors’ supervision)



19.  You are on a low sodium diet. (OK under doctors’ supervision)

If you are on this list, you should not take a lithium supplement without first educating yourself, consulting your doctor, or an expert in lithium administration/supplementation.

Will a small serving of lithium orotate be enough to effectively manage a moderate to severe mood disorder such as bipolar disorder, depression, anxiety, premenstrual syndrome?

While many individuals report significant improvements of their mood from low dose lithium, managing a moderate to severe mood disorder requires larger servings of lithium orotate to bring about the significant reduction in the severity of the symptoms.

What if I have a bad reaction to lithium orotate?

If it persists, reduce the amount of lithium. If the issue continues at the lowest serving amount, then lithium may not be for you.

Again, the good news in most published studies is, low dose lithium has a high positive response rate. At the lowest servings there should be no real issues at all. Relax and enjoy the process.

Is micro dosing and low dose (aka small serving sizes) lithium orotate, safe and free of side effects or adverse reactions for most people?

Yes it most certainly is, particularly when you begin at 1 mg or less

All side effects and adverse reactions are due strictly, to exceeding an individual’s tolerance (due to their unique biochemical individuality) to the amount of lithium they are taking. When lithium levels are reduced the side effects disappear.

How much lithium orotate should you begin with?

 We encourage everyone to begin with a very conservative microdose of 50-250mcg. A good guide is to take approx. 1-2 micrograms (mcg) per lb. of body weight.  We provide more options, and provide greater detail within the Micro-dose and Low-dose Lithium workbook.

Which product should I choose to begin this process?

You have several options to begin microdosing. You can begin with liquid drops, or a 1mg capsule. We provide more options, and provide greater detail on our Recommended Products Page and within the Micro-dose and Low-dose Lithium workbook.

What are the common side effects from taking too much lithium?

With low-dose lithium, side effects are very rare.

However due to wide variation in individual responses, particularly in sensitive individuals, with higher lithium levels, it is possible to see the following: drug interactions, hyper-urination with excessive thirst, nausea, mild tremor of hand, confusion or clouded thinking, and dizziness. If you experience any of these effects, reduce your lithium levels for relief.  Most side effects and adverse reactions resolve within 24 hours.

Is there an RDA for daily lithium supplementation?

There is no official RDA, as no essential function of lithium has been determined in humans, however, nutritional researcher Dr. Schrauzer (Schrauzer 2002) has suggested 1mg/day. Dr. Schrauzer was the first to suggest that lithium may be an essential element to optimal functions in animals and perhaps even humans.

Are there any concerns I should be aware of before I begin microdosing?

None published or experienced in the field. When taken at 1-2mcg per lb. of body weight there are no known adverse reactions or side effects. It is much more common to feel nothing in the beginning, and slowly over time, the lithium servings gradually get to a level, where you begin to feel lithium’s personal benefit to you.

What happens if I quit taking it suddenly?

If you have only been microdosing for a short while, you should feel fine, but over time, you may start to reexperience your old symptoms, returning. It’s better to reduce levels slowly.

Stopping abruptly (particularly in moderate/severe mood disorders) can be challenging and a risk for an abrupt return of acute symptoms. So, it is not advisable without your physician’s guidance.

What if I cannot afford to see a physician or pay for a consultation?

 If you must do this on your own, then you must educate yourself, so you don’t make mistakes. In this case, you may consider using only small servings of lithium orotate, particularly

if you are on the Contra-indications list. If you are not on the Contra-indications list, then you should increase your lithium by no more than 1mg/day. This way, you should not experience serious side effects, and you will minimize adverse reactions.

How soon can I take larger servings of lithium orotate?

Before you graduate to the higher servings of lithium orotate for greater improvement of mood or other conditions, you most certainly should consult a physician who is using lithium in their practice, or a wellness consultant that, at least is very familiar with how it works, and understands all the appropriate lab tests upon the kidney, thyroid and parathyroid glands.



Is lithium the overall best treatment for bipolar disorder?

Yes! Lithium is the Gold standard of care for bipolar disorder (BD). Lithium provides significant results for approximately 70% of this population. Lithium is one of the only treatments that is effective as a single solitary treatment without requiring other additional medication to prevent mania and depressive episode relapse. Spanning over 50 years of extensive research and FDA Approval we know all the pros and cons. In a broad and deep meta-analysis covering 17 leading pharmaceuticals, lithium was found to be the overall number #1 most effective mood stabilizer, for the treatment of bipolar disorder and manic-depressive episodes.

Mark Millar D.C., is a retired Chiropractor, and wellness coach, with extensive experience in the field of holistic and

natural healthcare. The recommendation and materials on this site represent his opinion based on his years of

practicing Chiropractic and decades of studying Neuropathy.

The information and material provided on this site are for educational purposes only

and any recommendations are not intended to replace the advice of your physician.

You are encouraged to seek advice from a competent medical professional regarding the applicability of any

recommendations with regard to your symptoms or condition. It is important that you do not reduce, change or

discontinue any medication or treatment without consulting your physician first. The personal stories shared on this

website are personal to the users and will not be typical of the results you will have if you follow the advice

provided on this website. 

The information and recommendations provided on this website have not been evaluated by the Food and Drug

Administration and are provided for

Educational purposes only

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